Do You Know How CBD Can Affect Our Endocannabinoid System?

Nowadays, most of us are quite familiar with CBD, as it can offer a number of health benefits. Indeed, it can bring positive impact on our physical as well as mental symptoms. While looking at all the working of CBD in detail, we come to know that CBD and our endocannabinoid system (ECS) can work together.

Such kind of interactions in our body will regulate few vital functions and also produce such kind of impressive results.

CBD oil and endocannabinoid system

Many of you probably may not be aware that all of us have endocannabinoid system. Actually, its name has come from the plant, which led to this discovery. When any CBD product improves your health, then it is actually interacting with your ECS.

In order to be little more specific, our human body has few cannabinoid receptors. As we consume CBD oil, this substance will change into metabolites. Then it binds to our endocannabinoid receptors.

They are named as receptor CB1 and CB2. This CBD endocannabinoid system reacts with our CB1, CB2 receptors for delivering a chain reaction. All these processes are necessary for our survival.

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CB1 receptor

During the year 1990, CB1 receptors was first discovered and it exist in very high numbers in our brain, central nervous system, intestines, gonads, various other glands and also connective tissues.

Benefits of activating our CB1 receptor are:

• Decreasing intestinal permeability
• Increasing BDNF levels
• Increasing myelin formation
• Increasing PPARy expression
• Lowering anxiety
• Lowering blood pressure
• Lowering intestinal inflammation
• Lowering prolactin
• Relieving depression
• Reducing GPR55 signaling
• Reducing paranoia and fear

While all these are for most people can be desirable effects, but CB1 receptor activation may not come without any risks which are:

• Constipation
• Decreased cognitive function
• Increased anxiety for those facing alcohol withdrawal
• Increased food intake
• Increased liver fat
• Less fat burning for energy
• Lowered thyroid hormones
• Reduced ability of circadian timekeeper to entrain daylight

Few other neurological symptoms can also be like:

• Depersonalization
• Delusion
• Hallucinations
• Impairment in memory and attention
• Paranoia

You may please note here that all these are side effects often associated with regular consumption of potent CB1 receptor like THC, but not with any non-psychoactive substance like CBD.

CB2 receptor

During the year 1993, CB2 receptors were discovered and occur mostly in

• Spleen
• Thymus
• Tonsils

Also, it can occur in the immune cells like:

• B and T cell
• Macrophages
• Mast cells
• Microglia
• Monocytes
• Small number in brain

Changes in your CB2 receptor will function which is synonymous with all kinds of human diseases whether it is:

• Autoimmune
• Cardiovascular
• Gastrointestinal
• Neurodegenerative and
• Psychiatric

Also, it can even play certain role in our kidney and liver function, skin and bone health, cancer, and other pain-related illnesses.

By activating your CB2 receptor it can induce macrophages for destroying the beta-amyloid protein that is main component of plaque, found in brain of those with Alzheimer’s disease.